![]() ![]() aeruginosa collected from diverse growth stages and with QS mutants. QS molecules bind to AhR and distinctly modulate its activity. We describe a pattern of regulation in the host by the aryl hydrocarbon receptor (AhR) that is critically dependent on qualitative and quantitative sensing of P. QS molecules can also be sensed by hosts, although the respective receptors and signaling pathways are poorly understood. Pseudomonas aeruginosa rapidly adapts to altered conditions by quorum sensing (QS), a communication system that it uses to collectively modify its behavior through the production, release, and detection of signaling molecules. 14 Hagler Institute for Advanced Study at Texas A&M University, College Station, TX 77843, USA.13 Institute of Functional Interfaces, Karlsruhe Institute of Technology, Karlsruhe, Germany.12 Protein Purification Core Facility, Max Planck Institute for Infection Biology, 10117 Berlin, Germany.11 Microarray Core Facility, Max Planck Institute for Infection Biology, Department of Immunology, 10117 Berlin, Germany.10 Epiontis GmbH-Precision for Medicine, 12489 Berlin, Germany.9 Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany.8 Faculty of Mathematics and Natural Sciences, University of Greifswald, Greifswald, Germany. ![]() 7 Institute of Immunology, Friedrich-Loeffler Institut, Greifswald-Insel Riems, Germany.6 Faculty of Mathematics, Informatics and Natural Sciences, University of Hamburg, 20148 Hamburg, Germany.5 Department of Structural Infection Biology, Centre for Structural Systems Biology, Helmholtz Centre for Infection Research (HZI), 22607 Hamburg, Germany.4 Structural Systems Biology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany.3 Department of Immunology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany. ![]() 2 Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, UK.
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